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An estimated 1.25 million people are chronically infected with HBV in the U.S., with 20 to 30% acquiring their infection in childhood (CDC) |
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Approximately 78,000 new HBV infections occur every year (CDC) |
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15-25% of chronically infected persons will die from liver disease |
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Chronic HBV infection occurs in: |
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90% of infants infected at birth |
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30% of children infected at age 1-5 years |
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6% of persons infected after age 5 years |
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Highest rate of disease occurs in 20-49 year-olds |
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30% of infected individuals are asymptomatic - symptoms are less common in children than adults (CDC) |
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Concurrent chronic HBV/HCV infection appears to increase the risk of progressive liver disease (NIH consensus statement) |
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An estimated 3.9 million people have been infected in the U.S. with HCV |
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Approximately 36,000 new HCV infections occur every year (CDC) |
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HCV is the most common chronic blood borne infection in the U.S. (CDC) |
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10,000 to 12,000 deaths yearly are attributed to HCV in the U.S. (NIH Consensus Statement) |
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30 to 40% of chronically infected persons are asymptomatic and have normal ALT levels (CDC) |
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A four-fold increase in the number of adults diagnosed with HCV is projected from 1990 to 2015 (NIH consensus statement) |
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60 to 85% of HCV infected individuals develop chronic infection (NIH Consensus Statement) |
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HCV is the primary reason for liver transplantation in the U.S. (NIH Consensus Statement) |
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HCV is the leading cause of death in HIV/HCV co-infected patients |