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ALPHA-1-ANTITRYPSIN QN

Test Code

235

CPT Code(s)

82103

Preferred Specimen(s)

1 ML SERUM

INSTRUCTIONS:
ALLOW BLOOD TO CLOT IN THE ORIGINAL CLOSED CONTAINER AT
ROOM TEMPERATURE (USUALLY 20 TO 30 MINUTES). AFTER CLOT
HAS FORMED, CENTRIFUGE BLOOD 10 MINUTES AT A RELATIVE
CENTRIFUGAL FORCE (CRF) OF 850 TO 1000 G IN THE STOPPERED
CONTAINER.

OVERNIGHT FASTING IS PREFERRED.

Minimum Volume

0.5 ML

Alternative Specimen(s)

SERUM COLLECTED IN:
SST (RED-TOP/PLASTIC)

Transport Container

SERUM SEPARATOR TUBE (SST)

Transport Temperature

ROOM TEMPERATURE

Specimen Stability

ROOM TEMPERATURE: 72 HOURS
REFRIGERATED: 7 DAYS
FROZEN: 90 DAYS

Reject Criteria

SST (RED-TOP/GLASS)

Methodology

FIXED RATE TIME NEPHELOMETRY

Performing Laboratory

QUEST DIAGNOSTICS/NICHOLS SJC
33608 ORTEGA HWY
SAN JUAN CAPISTRANO CA 92675-2042

Setup Days

MONDAY - SATURDAY

Clinical Significance

CONGENITAL DEFICIENCY OF ALPHA-1-ANTITRYPSIN (AAT) IS
ASSOCIATED WITH EARLY LUNG DISEASE (EMPHYSEMA, CHRONIC
BRONCHITIS, AND CHRONIC OBSTRUCTIVE LUNG DISEASE) AND
NEONATAL HEPATITIS AND INFANTILE CIRRHOSIS. IF A DEFICIENCY
IS PRESENT, AAT PHENOTYPING IS SUGGESTED TO CONFIRM
HETEROZYGOUS VERSUS HOMOZYGOUS DEFICIENCIES.

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

LOINC assignment is based on a combination of test attributes, including the method used by the performing laboratory. For tests not performed by Quest Diagnostics, codes are assigned by the performing laboratory.

* The tests listed by specialist are a select group of tests offered. For a complete list of Quest Diagnostics tests, please refer to our Directory of Services.